People on hypnotics, tranquilizers and analgesics that contain opiate should stay away from Tramadol.
If you are under medication of MAO inhibitors like parnate, eldepryl, emsam, marplan, nardil, selegiline, linezolid, isocarboxide, furazolidone, tranylcypromine, rasagiline, imoclobemide, procarbazine etc then you must not take tramadol. You must stop having the MAO inhibitors two weeks before you start having tramadol and once you are over with the course of tramadol after two weeks then you can again start your MAO inhibitors.
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Moreover, if you have been using any herbal products for your health then also you need to discuss this with the doctors before you start having the tramadol dosage.
If you want to avoid the risk of the serotonin syndrome then you must avoid other drugs. Your doctor must have complete information of your entire medication process and medical case history. If you are taking medicines for increasing the level of serotonin then also you need to discuss this with the doctor.
Tramadol Interactions
If you are under the strong medication of lithium, Street drugs, Citalopram, Dextromethorphan, Paroxetine, Sibutramine, Duloxetine, Migraine attack medicines like Triptans, Venlafaxine, Sumatriptan then you must avoid the use of tramadol as it might increase the chances of serotonin syndrome.
If you are having medicines like Phenothiazines, Isoniazid, Amitriptyline, Theophyline then you must avoid tramadol as in these cases if the particles of tramadol get mixed with the above medicines then it can lead to severe seizures.
There are certain drugs which will remove the tramadol medicine from your body such as Macrolide, Azole Antifungals, seizure related antibiotics, rifamycins and St john wort. These remove the tramadol particles from your body and thus you won’t get proper result of tramadol, moreover the conjunction of tramadol with other drugs can lead to severe side effects.
Anti drowsiness medicines like diphenhydramine, medicines that cure problem like anxiety like diazepam, seizure antibiotics like phenytoin, sleeping pills like zolpidem and cyclobenzaprine, which is a muscle pain reliever, can cause major problems if you are taking them with tramadol. So, if you are on a course of any of these medicines then you must inform your doctor and wait for his or her permission to have tramadol. Also, if you have normal medicines for cough and cold then you must read the labels of the medicines carefully. Some of these medicines may have ingredients that can lead to drowsiness. And, if you are already having tramadol then the side effects can be more potent.
Medicines that work as Antidepressant like Celexa, Elavil, Norpramin, Anafranil, Tofranil, Lexapro, Luvox, Zoloft, Pamelor, Paxil etc affect the work of tramadol badly.
Tegretol, lanoxin, nizoral, coumadin, lanoxicaps, St john wort, Rifater, Ery-tab, Rifadin, e-Mycin, Rimactane, E.E.S, Quinora, Quinaglute, pain medicines and cold medicines which causes drowsiness, seizures medicines, medicines that work for depression and also for anxiety should be avoided while taking Tramadol.
These are some of the medicines that have an adverse affect on the human body if consumed with tramadol. So, if you are taking any of these medicines make sure that you inform your doctor beforehand.