The risk of seizure is more in patients who take a higher dosage of TRAMADOL, especially if the patient is taking serotonin inhibitors like anorectics or SSRI antidepressants, TCAs, tricyclic compounds, opioids. Also patients taking medicines to reduce the problem of seizure, narcoleptics and inhibitors of MAO can face severe seizure problems if they are under the administration of TRAMADOL.
If a person has problems like epilepsy, history of seizure problems or facing disorders of metabolis, trauma of head, or drugs or alcohol withdrawal problem then they can face severe seizure problems if they intake TRAMADOL.
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Moreover, alcoholic patients, patients with depression or suicidal attitude, those who consume antidepressant drug or tranquilizers should not go on an TRAMADOL course. It is very risky and many unwanted death incidents have happened. These kinds of patients must have non narcotic analgesics; and tramadol must be used in a safe mode as prescribed by their doctors.

Tramadol Warning